When their friend Cookie OD's best buddies and musicians Spoon (Tupac Shakur) and Stretch (Tim Roth) decide it's time to kick their drug habit by putting themselves into detox. But they soon discover that the road to rehab is paved with reams of social service red tape. Spoon and Stretch are just trying to stay alive until they can get treatment. But between the angry drug dealers the cops who have mistaken them for murderers and the people with forms and clipboards this turns into a task of epic proportions. Thus enfolds their comic adventure to sobriety.
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Heroin addicts Stretch (Tim Roth) and Spoon (Tupac Shakur) make a New Year's resolution to kick the habit after their friend and fellow band member Cookie goes into a coma. After stealing some money from crime figure D-Reper, they go to their dealer and find him murdered. Scavenging drugs and money, they go on the run and attempt to book into a detox clinic, all the while pursued by D-Reper and the police, who are investigating the dealer's death.
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